480-11-5
- Product Name：Oroxylin A
- Molecular Formula：C16H12O5
- Purity：99%
- Molecular Weight：284.268
Reputable factory supply Oroxylin A 480-11-5 in bulk at low price
- Molecular Formula:C16H12O5
- Molecular Weight:284.268
- Vapor Pressure:2.6E-12mmHg at 25°C
- Melting Point:195-197oC
- Refractive Index:1.6200 (estimate)
- Boiling Point:540.9°Cat760mmHg
- PKA:6.48±0.40(Predicted)
- Flash Point:207.4°C
- PSA：79.90000
- Density:1.42g/cm3
- LogP:2.87980
Oroxylin(Cas 480-11-5) Usage
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Definition |
ChEBI: A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-6. |
InChI:InChI=1/C16H12O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5-3-2-4-6-9/h2-8,18-19H,1H3
480-11-5 Relevant articles
5,6,7-TRISUBSTITUTED FLAVONES FROM GOMPHRENA MARTIANA
Buschi, C. A.,Pomilio, A. B.,Gros, E. G.
, p. 1178 - 1179 (1981)
Two 5,6,7-trisubstituted flavones have b...
Flavonoids from Scutellaria phyllostachya roots
Siddikov,Yuldashev,Abdullaev
, p. 324 - 325 (2007)
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An unambiguous and practical synthesis of Oroxylin A: a commonly misidentified flavone
Hemantha, Hosahalli P.,Ramanujam, Rajendran,Majeed, Muhammed,Nagabhushanam, Kalyanam
, p. 1413 - 1420 (2019/08/22)
Oroxylin A, a major flavonoid in the ext...
Crystal structures of the flavonoid Oroxylin A and the regioisomers Negletein and Wogonin
Grano, Ruel Valerio Robles De,Nisar, Madiha,Sung, Herman H.-Y.,Vashchenko, Elena V.,Vashchenko, Valerii V.,Williams, Ian D.
, p. 490 - 499 (2020/05/18)
The flavonoid Oroxylin A (6-methoxychrys...
Synthetic method of oroxylin
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, (2020/05/14)
The invention relates to a synthetic met...
Process for Preparing Oroxylin A
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Paragraph 0033-0038, (2019/03/08)
A process for preparing oroxylin A inclu...
480-11-5 Process route
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- 82475-02-3
5-hydroxy-6-methoxyflavone-7-O-β-D-glucuronide methyl ester
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- 480-11-5
oroxylin A
Conditions
| Conditions | Yield |
|---|---|
|
With sulfuric acid; In water; at 100 ℃; for 3h;
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73% |
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With sulfuric acid; In water; at 100 ℃; for 3h;
|
72% |
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With sulfuric acid; In water; at 99.84 ℃; for 4h;
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26% |
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- 21967-41-9,27462-75-5,31564-28-0
baicalin
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- 480-11-5
oroxylin A
Conditions
| Conditions | Yield |
|---|---|
|
baicalin; With potassium carbonate; dimethyl sulfate; at 20 ℃; for 24h;
With hydrogenchloride; In ethanol;
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56% |
|
baicalin; With potassium carbonate; dimethyl sulfate; at 20 ℃;
With hydrogenchloride; In ethanol; at 80 ℃; for 10h;
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56% |
|
Multi-step reaction with 6 steps
1: water; sulfuric acid / 0.67 h / 121 °C
2: sodium acetate / 0.67 h / 40 °C
3: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C
4: water; sodium hydroxide; sodium dithionite / methanol / 16 h / 20 °C
5: potassium carbonate / N,N-dimethyl-formamide / 21 h / 20 °C
6: water; hydrogenchloride / N,N-dimethyl-formamide / 0.17 h / 20 °C
With hydrogenchloride; sodium dithionite; sulfuric acid; water; sodium acetate; potassium carbonate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;
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Multi-step reaction with 3 steps
1: sulfuric acid / tetrahydrofuran / 6 h / 80 °C
2: potassium carbonate / N,N-dimethyl-formamide / 20 °C
3: sulfuric acid / water / 3 h / 100 °C
With sulfuric acid; potassium carbonate; In tetrahydrofuran; water; N,N-dimethyl-formamide;
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Multi-step reaction with 3 steps
1: sulfuric acid / methanol; tetrahydrofuran / 6 h / 80 °C
2: potassium carbonate / N,N-dimethyl-formamide / 20 °C
3: sulfuric acid / water / 3 h / 100 °C
With sulfuric acid; potassium carbonate; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;
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|
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Multi-step reaction with 3 steps
1: sulfuric acid / tetrahydrofuran / 79.84 °C
2: potassium carbonate / N,N-dimethyl-formamide / 20 °C
3: sulfuric acid / water / 4 h / 99.84 °C
With sulfuric acid; potassium carbonate; In tetrahydrofuran; water; N,N-dimethyl-formamide;
|
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